Early Detection of Type 1 Diabetes and Celiac Disease in Children
Sanford Health has made a strong commitment to studying, preventing and curing type 1 diabetes (T1D). The Sanford PLEDGE study is a large-scale screening of children for T1D and celiac disease.
Through PLEDGE, we hope to find better ways to identify which children may be at risk of developing these diseases. Early detection and ongoing monitoring means kids could start treatment early enough to prevent serious illness.
Who can Join the PLEDGE Study?
Children who:
- Are ages 0-5 or ages 9-16
- Do not have T1D
- Receive routine care at Sanford Health
- Have a My Sanford Chart account
Children ages 6 to 17 who have a sibling with T1D or T1D antibodies may also join the study.
How PLEDGE Works
You’ll complete these steps in My Sanford Chart:
- Give permission for your child to participate in the study and provide access to their medical records.
- Complete brief questionnaires about your child’s and your family’s medical history.
The Sanford PLEDGE study will also collect a small amount of blood when your child is in for routine care. The number of blood draws will depend on your child’s age when they entered the study.
We test the samples for:
- A genetic risk score (GRS) that may show if a child is at a higher risk for T1D or celiac disease.
- T1D and celiac antibodies, which are early signs of these diseases.
Learn More
Type 1 Diabetes
Type 1 diabetes is a chronic disease that can cause serious health issues. Learn about the condition and how our study hopes to identify it early.
Celiac Disease
The PLEDGE study aims to help children with celiac disease get care sooner through early detection. Read more about the disease and its symptoms.
PLEDGE Stories
Meet Gary Hall Jr.
The Olympic swimmer hasn’t let a diabetes diagnosis slow him down. Learn how the 10-time medal winner is working to advance diabetes research.
Meet the Jensen Family
Maren Jensen enrolled her daughter, Blakely, in the PLEDGE study for Blakely’s welfare – and to support diabetes research.
Meet Drs. Griffin and Whittington
Kurt Griffin, MD, and Laura Whittington, DO, discuss why children should enroll in the PLEDGE study and how to start the process.